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Diosmin:Hesperidin

Botanical Name:

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Diosmin:Hesperidin

Diosmin:Hesperidin

Diosmin:Hesperidin

Product name: Pharmaceutical grade Diosmin powder

Diosmin:Hesperidin = 90:10 

Specification: Diosmin 90 : 10 hesperidine

Appearance: Yellow fine powder

Mesh size: 80 Mesh

Used Part: fruit

Grade: Pharmaceuticals Ingredients


Product description:

Diosmin is a naturally occurring flavonoid glycoside that can be isolated from various plant sources or derived from the flavonoid hesperidin. Diosmin was first isolated in 1925 from Scrophularia nodosa, and first introduced as a therapeutic agent in 1969. Diosmin is a biogenic amine derived by extracting hesperidin from Citrus Aurantium L., followed by conversion of hesperidin to diosmin. Diosmin is considered to be a vascular-protecting agent used to treat chronic venous insufficiency, hemorrhoids, lymphedema, and varicose veins. As a flavonoid, diosmin also exhibits anti-inflammatory, free-radical scavenging, and antimutagenic properties. Diosmin has been used for more than 30 years as a phlebotonic and vascularprotecting agent, and has recently begun to be investigated for other therapeutic purposes, including cancer, premenstrual syndrome, colitis, and diabetes.


Product benefits:

1.Diosmin prolongs the vasoconstrictor effect of norepinephrine on the vein wall, increasing venous tone, and therefore reducing venous capacitance, distensibility, and stasis.

2.Diosmin increases the venous return and reduces venous hyperpressure present in patients suffering from CVI.

3.Diosmin improves lymphatic drainage by increasing the frequency and intensity of lymphatic contractions, and by increasing the total number of functional lymphatic capillaries.

4.Diosmin with hesperidine decreases the diameter of lymphatic capillaries and the intralymphatic pressure.

5.At the microcirculation level, diosmin reduces capillary hyperpermeability and increases capillary resistance by protecting the microcirculation from damaging processes.

6.Diosmin reduces the expression of endothelial adhesion molecules,and inhibits the adhesion, migration, and activation of leukocytes at the capillary level.Diosmin leads to a reduction in the release of inflammatory mediators, principally oxygen free radicals and prostaglandins.